Overview
PDE5 inhibitor for erectile/vascular function; pairs with PT-141 (central + vascular arousal). Also used low-dose daily for vascular healthspan.
How it works
- PDE5 inhibition → ↑ cGMP → vasodilation
Dosing
Daily 2.5–5 mg, or PRN 10–20 mg.
Oral5 mg standardrange ·–20 mg· daily or PRN
Cycling
- Continuous or on-demand
Side effects
- Common
- Headache
- Flushing
- Nasal congestion
- Warnings
- Contraindicated with nitrates
Verified citations
2 · PubMed-checked- Direct comparison of tadalafil with sildenafil for erectile dysfunction: meta-analysis.clinicalPMID 28741090
- Tadalafil in the treatment of erectile dysfunction.reviewPMID 14622501
Reconstitution
Not applicable · this compound is oral. No vial reconstitution needed.
Legal / compounding
FDA-approved
FDAApproved
Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.